Peptides, Part 2: Copper GHK’s Role in Healing & Regeneration
About this episode
In this episode, Dr. Jim Chialtas discusses the role of Copper GHK in healing and regeneration, covering its effects on repair, aging, and gene expression.
In this 166th episode, I continue with my mini-series on peptide therapies and discuss Copper GHK. Copper GHK is a small copper-bound tripeptide that affects repair, aging, and gene expression. I cover its natural role in plasma and tissues, how levels fall with age, and the surprising breadth of its actions—from extracellular matrix remodeling and antioxidant effects to cognitive protection, cardiovascular benefits, and boosted wound healing. I also walk through the molecular mechanisms, real-world applications, and practical considerations for clinicians and listeners interested in regenerative support. Citations: 1. Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int.2015;2015:648108. doi: 10.1155/2015/648108. Epub 2015 Jul 7. PMID: 26236730;PMCID: PMC4508379. 2. Pickart L, Margolina A. The Effect of the Human Plasma Molecule GHK-Cu on Stem Cell Actions and Expression of Relevant Genes. OBM Geriatrics 2018;2(3):009;doi:10.21926/obm.geriatr.1803009. 3. Adnan SB, Maarof M, Fauzi MB, Fadilah NIM. Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive…
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