Reimagining Renal Assessment: Pros and Cons - Ep 182
From ACCP JOURNALS by ACCP JOURNALS
May 12, 2026 · 38 min
About this episode
The episode discusses the adoption of race-free estimated GFR for kidney function assessment in older adults, highlighting the limitations of the Cockcroft–Gault equation.
JACCP associate editor and host, Erica Ernst, interviews Drs. Wendy St. Peter and Barbara Zarowitz discuss adopting race-free estimated GFR (CKD-EPI) for medication-related kidney function assessment in older adults and other patient populations, as well as moving away from the Cockcroft–Gault equation. The discussion highlights deficiencies and variabilityin Cockcroft–Gault use, emerging studies where BSA-adjusted eGFR better predicts drug clearance, barriers to cystatin C access and Medicare coverage, and the need for further research, electronic health record integration, and advocacy across organizations. Read the original article and series of letters published in JACCP.
People in this episode
Host: Erica Ernst
Guests: Wendy St. Peter, Barbara Zarowitz
Topics covered
- renal assessment
- medication-related kidney function
- race-free estimated GFR
- Cockcroft–Gault equation
- drug clearance
- cystatin C access
- healthcare advocacy
Keywords
- renal assessment
- GFR
- CKD-EPI
- Cockcroft–Gault
- cystatin C
- drug clearance
- older adults
- health records
- advocacy
- Medicare
Mentioned in this episode
Organizations: JACCP, Medicare, CKD-EPI, Cockcroft–Gault
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