
Psilocybin's potential in treating methamphetamine use disorder with Jonathan Brett
From Addiction Audio by Addiction journal
March 6, 2026 · 20 min · Season 4 · Episode 8
About this episode
Dr Elle Wadsworth interviews Professor Jonathan Brett about the potential of psilocybin in treating methamphetamine use disorder.
In this episode, Dr Elle Wadsworth talks to Professor Jonathan Brett, a senior consultant at St. Vincent’s Hospital, Sydney, clinical director of the Psychiatry and Non-Prescription Drug and Alcohol Unit, and a clinical toxicologist with the New South Wales Poison’s Information Centre, Australia. The interview covers Jonathan’s research article looking at psilocybin-assisted psychotherapy for methamphetamine use disorder: A pilot open-label safety and feasibility study Psilocybin and what psilocybin-assisted psychotherapy looks like [01:20] Why look at methamphetamine use disorder? [04:38] Why is psilocybin promising for methamphetamine use disorder? [06:21] Explaining the single-arm open label pilot trial [09:35] The key findings of the study [10:54] The efficacy of psilocybin for methamphetamine use disorder treatment [12:12] The implications of the findings for policy and practice [14:50] The increased interest in psychedelics and a note of caution [17:03] About Elle Wadsworth: Elle is an academic fellow with the Society for the Study of Addiction. She is based at the University of Bath with the Addiction and Mental Health Group and her research interests include drug policy…
People in this episode
Host: Dr Elle Wadsworth
Guest: Professor Jonathan Brett
Topics covered
- psilocybin
- methamphetamine use disorder
- psychotherapy
- addiction medicine
- clinical research
- psychedelics
Keywords
- psilocybin
- methamphetamine
- addiction treatment
- clinical trial
- psychotherapy
- safety study
- feasibility study
- psychedelics
- drug policy
Mentioned in this episode
Organizations: St. Vincent’s Hospital, New South Wales Poison’s Information Centre, Society for the Study of Addiction
Books & works: Psilocybin-assisted psychotherapy for methamphetamine use disorder: A pilot open-label safety and feasibility study
Places: Sydney, Australia
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