E209: Beyond Failure Prevention: How AI is Redesigning the Drug Discovery Pipeline
About this episode
The episode discusses how AI is transforming drug discovery by integrating diverse biological data and improving patient stratification.
AI in drug development is moving beyond “failure prevention” into something much bigger: redesigning how we discover, develop, and deliver medicines. In this episode, Dr Andree Bates speaks with Vitalay Fomin of Numenos about biomarker discovery, patient stratification, and why the next breakthroughs come from breaking down data silos across diseases, modalities, and even species. Vitalay shares his background across biotech and pharma, including work in biomarker discovery, translational medicine, and data science, and how frustration with existing approaches led her to build a new architecture for clinical genomic insights. A core theme is that traditional methods often oversimplify biology by forcing outcomes into binary labels and treating each disease area as an isolated box, even when the available data is too limited to answer meaningful questions well. The conversation explores how foundation model approaches can unify clinical, genomic, transcriptomic, proteomic and imaging signals to create a fuller “biological fingerprint” of each patient. Vitalay explains how this can enable earlier insight from single-arm trials by effectively benchmarking against standard-of-care…
People in this episode
Host: Dr Andree Bates
Guest: Vitalay Fomin
Topics covered
- AI in drug development
- biomarker discovery
- patient stratification
- data silos
- clinical genomic insights
- foundation model approaches
Mentioned in this episode
Organizations: Numenos, Big Pharma
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