Mixing Local Anesthetics: Smart Shortcut or Hidden Risk?
From Anesthesia Updates by NYSORA
April 13, 2026 · 10 min · Season 1 · Episode 80
About this episode
This episode discusses the safety and efficacy of mixing local anesthetics based on a 2026 study.
Mixing lidocaine, ropivacaine, and bicarbonate is routine in many hospitals, but is it actually safe? In this episode, we discuss the main findings from a 2026 article by Gasteiger et al. (Anesthesiology), which questions the stability, efficacy, and safety of common local anesthetic mixtures. From crystal formation to reduced block performance, we explore why combining drugs may do more harm than good, and how to rethink this everyday practice. Read more about this on NYSORA.com . =========================================== Where else to find us: Web - LINK Instagram - LINK LinkedIn - LINK Facebook - LINK Twitter - LINK TikTok - LINK --------------------------------------------------------- #nysora #regionalanesthesia #anesthesia Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available…
People in this episode
Host: NYSORA
Topics covered
- local anesthetics
- safety
- drug mixing
- anesthesia practice
- medical research
Keywords
- lidocaine
- ropivacaine
- bicarbonate
- local anesthetic mixtures
- anesthesia safety
Mentioned in this episode
Organizations: NYSORA
Books & works: Anesthesiology
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