Episode 57: Autoinflammatory Diseases with Adult Rheumatologist Dr. Jason An
About this episode
The episode discusses autoinflammatory diseases, their differences from autoimmune diseases, and practical approaches for diagnosis and treatment in adults.
Autoinflammatory diseases are often considered rare — but, in clinical practice, they may be far more common than we think. In this episode of Around the Rheum, hosts Dr. Daniel Ennis and Dr. Janet Pope speak with Dr. Jason An, a Toronto rheumatologist with expertise in autoinflammatory disorders. Together, they explore how these conditions differ from classic autoimmune disease, why adult rheumatologists should be thinking about them more often, and how to approach diagnosis when the presentation doesn’t fit neatly into familiar categories. Dr. An also shares practical strategies for recognizing autoinflammatory patterns, interpreting genetic testing, and using targeted therapies both diagnostically and therapeutically. In this episode we discuss: The evolving definition of autoinflammatory disease and how it differs from autoimmune disease Why these disorders are not just pediatric diseases and may present in adulthood A practical cytokine-based framework for classifying autoinflammatory diseases The four major inflammatory “buckets”: IL-1–mediated diseases IL-18-mediated diseases TNF / NF-κB pathway disorders Interferonopathies Clinical pattern recognition in patients with…
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- Episode 58: ASM Roundup - Day 1 with Dr Marinka Twilt
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- Episode 55: Exploring the New CRA/CanRIO Guidelines with Dr. Carrie Ye and Dr. Jeff Graham
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