About this episode

Dr. Joshua Reuss discusses the update to the living guideline on stage IV NSCLC without driver alterations and its implications for treatment options.

Dr. Joshua Reuss is back on the podcast to discuss the full update to the living guideline on stage IV NSCLC without driver alterations. He discusses the new evidence and how this impacts the latest recommendations on first-line and subsequent therapeutic options. Dr. Reuss emphasizes the need for shared decision-making between clinicians and patients. He shares ongoing research that the panel will review in the future for further updates to this living guideline, and puts the updated recommendations into context for clinicians treating patients with stage IV NSCLC. Read the full living guideline update "Therapy for Stage IV Non-Small Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline, Version 2026.3.0" at www.asco.org/thoracic-cancer-guidelines " TRANSCRIPT This guideline, clinical tools and resources are available at www.asco.org/thoracic-cancer-guidelines . Read the full text of the guideline and review authors' disclosures of potential conflicts of interest in the Journal of Clinical Oncology, https://ascopubs.org/doi/10.1200/JCO-25-02825 Brittany Harvey : Hello and welcome to the ASCO Guidelines podcast, one of ASCO's podcasts delivering timely information to…

People in this episode

Host: Brittany Harvey

Guest: Dr. Joshua Reuss

Topics covered

• stage IV NSCLC
• living guidelines
• therapeutic options
• shared decision-making
• oncology updates

Keywords

• NSCLC
• driver alterations
• therapeutic options
• guideline update
• oncology

Mentioned in this episode

Organizations: American Society of Clinical Oncology, Georgetown University, Journal of Clinical Oncology

Books & works: Therapy for Stage IV Non-Small Cell Lung Cancer Without Driver Alterations: ASCO Living Guideline, Version 2026.3.0

Places: ASCO

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