Ep. 305 Immune Therapy Innovations for BCG Unresponsive Cancer with Dr. Sam Chang

About this episode

Dr. Ruchika Talwar hosts Dr. Sam Chang to discuss innovations in immune therapy for BCG-unresponsive non-muscle invasive bladder cancer.

Ready to move beyond “one-size-fits-all” for BCG-unresponsive NMIBC? In this episode of BackTable Urology, Dr. Ruchika Talwar hosts Dr. Sam Chang to discuss the evolving treatment landscape for BCG-unresponsive non-muscle invasive bladder cancer (NMIBC). They explore why BCG may fail, the science and clinical rationale behind new immunotherapies and gene therapies, practical approaches to patient selection, treatment sequencing, and surveillance, and the value of emerging biomarkers, empowering urologists to make more informed, personalized decisions in complex cases of NMIBC. --- Get the BackTable apphttps://www.backtable.com/app --- This podcast is supported by ImmunityBiohttps://anktiva.com/ --- Timestamps 00:00 - Introduction03:48 - BCG: How it Works and Why it Fails11:13 - Pembrolizumab Role and Limits14:38 - Nadofaragene firadenovec 16:34 - Cretostimogene grenadenorepvec18:39 - BCG + Anktiva Rationale29:50 - Explaining Options to Patients33:05 - Post Treatment Surveillance37:32 - Future of Biomarkers and AI42:05 - Key Takeaways --- Resources N-803 Plus BCG Treatment for BCG-Naïve or -Unresponsive Non-Muscle Invasive Bladder Cancer: A Plain Language…

People in this episode

Host: Dr. Ruchika Talwar

Guest: Dr. Sam Chang

Topics covered

• immunotherapy
• bladder cancer
• BCG-unresponsive cancer
• patient selection
• treatment sequencing
• biomarkers

Keywords

• BCG
• immunotherapy
• non-muscle invasive bladder cancer
• biomarkers
• treatment options
• patient care

Sponsors

ImmunityBio

Mentioned in this episode

Products: Anktiva, N-803, Pembrolizumab, Cretostimogene grenadenorepvec, Nadofaragene firadenovec

Places: BCG, NMIBC

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