Bugs As Drugs: A Journey into the Weird and Wonderful World of the Microbiome
About this episode
The episode explores the use of live microbes as therapies to rebalance microbiomes and the associated challenges in the field.
What are “ bugs as drugs ?” These are live microbes used as therapies designed to help rebalance our microbiomes, offering hope against everything from antibiotic-resistant infections to chronic diseases. But working with living organisms isn’t as simple as formulating a pill. These therapies raise deep scientific, regulatory, and manufacturing challenges. In this episode of Balancing the Future , Micah and Chai are joined by Dr. Moira Monika Schuler, Global Chemistry, Manufacturing, and Controls Manager at Wacker Biotech. Together, they explore how our microbiomes shape human health in ways we’re only beginning to understand. From gut disorders to mood regulation and hormone balance, the microbiome is emerging as a central player in 21st-century medicine. They dive into groundbreaking work like fecal microbiota transplants (FMTs), FDA-approved microbial therapeutics, and the race to develop safe and scalable live biotherapeutic products. But the conversation also touches on the many hurdles: ensuring consistency among living strains, developing complicated sterile delivery systems, and navigating a fragmented regulatory landscape across the U.S. and Europe. LINKS Dr. Moira…
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