
Clinical Challenges in Emergency General Surgery: C Diff - When to Pull the Operative Trigger
From Behind The Knife: The Surgery Podcast by Behind The Knife: The Surgery Podcast
June 1, 2026 · 33 min · Episode 134
About this episode
The episode discusses the critical decision-making process in emergency general surgery regarding fulminant Clostridioides difficile infection and when to opt for surgical intervention.
It’s hospital day five. The patient looked better yesterday… but now she’s hypotensive, on vasopressors, acidotic, and spiraling toward multi-organ failure. The CT scan doesn’t show perforation or megacolon, but your gut tells you this is going south. Do you keep pushing medical therapy… or is it time to operate? Join Drs. Rushabh Dev, Jeffrey Coughenour, Kevin Bartow, Raymond Okeke, and Desra Fletcher from the Emergency General Surgery team in Tiger Country at Mizzou as they tackle one of the deadliest and most challenging diseases acute care surgeons face: fulminant Clostridioides difficile infection . In this Clinical Challenges episode, the panel discusses diagnostic stewardship, ASCRS recommendations, timing of operative intervention and technique, subtotal colectomy versus diverting loop ileostomy with lavage, and physiology that should push surgeons toward definitive source control. Through a real-world high-risk case vignette, the team explores the hardest question in emergency general surgery: when to stop hoping medical therapy will work and pull the operative trigger. Hosts Dr. Rushabh Dev FACS (Moderator, Surgical Attending) – Assistant Professor of Surgery, Associate…
People in this episode
Hosts: Dr. Rushabh Dev, Dr. Jeffrey Coughenour, Dr. Kevin Bartow
Topics covered
- emergency general surgery
- Clostridioides difficile infection
- operative intervention
- diagnostic stewardship
- surgical techniques
- multi-organ failure
Keywords
- C Diff
- surgery
- vasopressors
- multi-organ failure
- subtotal colectomy
- diverting loop ileostomy
- diagnostic stewardship
Mentioned in this episode
Organizations: University of Missouri SOM, United States Navy Reserve
More episodes of Behind The Knife: The Surgery Podcast
- Clinical Challenges in Surgical Oncology: Melanoma · June 11, 2026 · 35 min
- Clinical Challenges in Vascular Surgery: Phlegmasia in Pregnancy · June 8, 2026 · 38 min
- Bad Day on Call: Live Case Discussion from ASGBI Conference · June 4, 2026 · 33 min
- BIG T Trauma Ep. 28: Retained Ballistic Fragments: What We Were Never Taught · May 28, 2026 · 27 min
- Journal Review in Surgical Education: What We Can Learn From America’s Literacy Crisis · May 25, 2026 · 25 min
- Journal Review in Colorectal Surgery: Methods for Ileocolic Anastomosis in Crohn's Disease · May 21, 2026 · 29 min
Explore listener stats, chart rankings, contacts and more on the Behind The Knife: The Surgery Podcast podcast page.