About this episode

The episode discusses the role of circulating tumor DNA in managing colorectal cancer and anal squamous cell cancer.

Circulating tumor DNA (ctDNA), a minimally invasive blood-based biomarker, has emerged as one of the most promising advances in cancer surveillance. Today, we will explore how ctDNA is transforming the management of colorectal cancer and anal squamous cell cancer across the disease continuum—from risk stratification and adjuvant therapy decision-making to surveillance and early detection of recurrence. Through landmark clinical trials, real-world applications, and emerging research, we will examine how ctDNA is helping move cancer care closer to the goal of truly personalized medicine. Hosts: · Dr. Janet Alvarez - General Surgery Resident at New York Medical College/Metropolitan Hospital Center · Dr. Wini Zambare – General Surgery Resident at Weill Cornell Medical Center/New York Presbyterian · Dr. Philip Bauer, Assistant Professor of Surgery, Division of Colon and Rectal Surgery, The Ohio State University Wexner Medical Center, Arthur G. James Cancer Hospital · Dr. J. Joshua Smith MD, PhD, Chair, Department of Colon and Rectal Surgery at MD Anderson Cancer Center Guests: Dr. Paul Romessor · Director of Colorectal and Anal Cancer, Department of Radiation Oncology · Associate…

People in this episode

Hosts: Dr. Janet Alvarez, Dr. Wini Zambare, Dr. Philip Bauer, Dr. J. Joshua Smith MD, PhD

Guests: Dr. Paul Romessor, Dr. Jeanne Tie, Dr. Takayuki Yoshino

Topics covered

• ctDNA
• colorectal cancer
• anal squamous cell cancer
• cancer surveillance
• personalized medicine

Keywords

• circulating tumor DNA
• ctDNA
• cancer management
• risk stratification
• adjuvant therapy
• surveillance
• recurrence detection

Mentioned in this episode

Organizations: Memorial Sloan Kettering Cancer Center, Peter MacCallum Cancer Centre, Global Center of Research Excellence

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