About this episode

This episode explores the foundational role of lipid biology and plasmalogens in cellular health and neurodegenerative patterns with guest Dayan Goodenowe, PhD.

🎧 Episode Summary This episode explores the foundational role of lipid biology and plasmalogens in cellular health, inflammation, and neurodegenerative patterns. Dayan Goodenowe, PhD discusses how membrane composition, oxidative stress, and environmental factors influence cellular function, along with the potential impact of plasmalogen precursor therapies on cognition, resilience, and overall system regulation. 🧭 In This Episode - Lipid membrane composition differences across cell types and organelles - Phospholipid bilayer structure and hydrophilic–hydrophobic organization - Functional role of membrane lipids in cellular compartmentalization - Variability of lipid composition within different regions of a single cell - Impact of oxidative stress on membrane lipid composition and function - Mechanism of phospholipid peroxidation and phospholipase-mediated removal - Relationship between membrane rigidity and cellular signaling capacity - Mitochondrial dysfunction and its role in the Cell Danger Response - Nutrient and cofactor requirements for mitochondrial energy production - Interaction between membrane lipid integrity and mitochondrial performance - Immune activation…

People in this episode

Host: Scott Forsgren

Guest: Dayan Goodenowe, PhD

Topics covered

• lipid biology
• plasmalogens
• neurodegenerative diseases
• cellular health
• oxidative stress
• mitochondrial dysfunction

Keywords

• lipid membrane composition
• phospholipid bilayer
• cell signaling
• mitochondrial performance
• immune activation
• plasmalogen precursors

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