NFL Week 1 Picks & Predictions: Best Bets for EVERY Game (Ep. 1048)

NFL Week 1 Picks & Predictions: Best Bets for EVERY Game (Ep. 1048)

August 28, 2026 · 51 min · Episode 1048

About this episode

Ryan Wormeli and Andrew Erickson analyze the betting lines and provide predictions for every game in NFL Week 1.

Week 1 is rapidly approaching! Ryan Wormeli and Andrew Erickson break down the early betting lines for the opening week of the 2026 NFL season, giving you their favorite NFL Week 1 picks, best bets, upset predictions, spreads, totals, moneyline plays and more. Which early NFL lines offer the most value? The guys go game-by-game through the Week 1 slate, looking for opportunities to grab closing line value (CLV) before the market moves. Some of the biggest debates include whether the Rams-49ers Australia matchup is screaming UNDER, why Houston could upset Buffalo, whether Jacksonville belongs in your Week 1 survivor pool, a Dolphins-Raiders upset pick, and whether Denver can knock off Patrick Mahomes and Kansas City at Arrowhead.

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