Breaking "Wine O'Clock": Psilocybin, Saffron, Microdosing and Upgrading Women's Mental Health with Keegan Downer

Breaking "Wine O'Clock": Psilocybin, Saffron, Microdosing and Upgrading Women's Mental Health with Keegan Downer

February 19, 2026 · 59 min · Episode 429

About this episode

Keegan Downer discusses his journey from addiction to recovery and the benefits of microdosing psilocybin for women's mental health.

Keegan Downer (Founder of mindfulMEDS ) shares how he went from alcohol addiction and a near-suicidal breaking point, to recovery and to building one of Canada's most recognized microdosing education brands, and why psilocybin doesn't have to be "woo." We also get super practical: What microdosing actually feels like day-to-day, why it can hit women differently (especially moms), how psilocybin compares to SSRIs (Selective Serotonin Reuptake Inhibitor) when it comes to emotional processing, and why "wine o'clock" culture is quietly keeping so many women stuck in a stress-and-numb cycle. Want protocols built specifically for women, live coaching, and real talk about peptides and longevity? That's what The LongHer Life is for. Private. Uncensored. Ongoing. https://biohackingbrittany.com/pages/longherlife WE TALK ABOUT: 05:40 - Keegan's life collapse that led to addiction and the "rooftop moment" 07:45 - Rebuilding purpose after rehab and the anxiety attack that changed everything 09:10 - Why microdosing went from "nobody's talking about this" to mainstream fast 12:35 - The day-13 breakthrough and the microdosing study that launched his mission 19:30 - Why psilocybin and SSRIs…

People in this episode

Host: Brittany Ford

Guest: Keegan Downer

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Mentioned in this episode

Organizations: mindfulMEDS, The LongHer Life

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