Unlocking Antibody Development with AI with Dr. Pin-Kuang Lai

About this episode

The episode explores the intersection of AI and molecular engineering in antibody development with Dr. Pin-Kuang Lai.

In this episode of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe interview Asst. Professor Pin-Kuang Lai from Stevens Institute of Technology about his keynote speech at AAPS NBC 2025 and the intersection of AI and molecular engineering, particularly in predicting the viscosity of monoclonal antibodies. They discuss the challenges of high concentration formulations, the importance of AI validation, and the future of formulation development. Lai shares insights from his international research journey and collaborations with pharmaceutical companies, as well as opportunities for students interested in this field. 00:00 Preview & Intro 01:58 Deep Viscosity and AI in Antibody Development 04:39 AI Validation and Model Reliability 07:12 International Journey and Collaborative Research 08:42 Future of Formulation Development 10:30 AAPS NBC Experience 11:30 Academic vs. Industry Career Paths 12:31 Collaboration with Pharmaceutical Companies 13:59 Modeling Protein Aggregation Challenges 14:43 Student Engagement and Research Opportunities 15:45 Expanding Applications of Machine Learning Dr. Pin-Kuang Lai https://www.linkedin.com/in/pin-kuang-lai/ Stevens Institute of…

People in this episode

Hosts: Dr. Chad Briscoe, Gregory Austin

Guest: Dr. Pin-Kuang Lai

Topics covered

• AI in antibody development
• molecular engineering
• formulation development
• pharmaceutical collaborations
• student research opportunities

Keywords

• antibody development
• AI validation
• monoclonal antibodies
• formulation challenges
• protein aggregation
• machine learning
• research opportunities

Mentioned in this episode

Organizations: Stevens Institute of Technology, Celerion

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