About this episode

Dr. Adrian Minson discusses the latest lymphoma developments from EHA and ICML 2025, focusing on bispecific antibodies and key clinical trials.

In this episode of Blood Cancer Talks, we have Dr. Adrian Minson from the Peter MacCallum Cancer Centre to discuss the latest developments in lymphoma presented at the recent EHA and ICML meetings in June 2025. The episode focuses primarily on the emerging role of bispecific antibodies in various combinations and treatment settings for diffuse large B-cell lymphoma (DLBCL). Key Clinical Trials Discussed 1. POLARGO Trial - Polatuzumab + R-GemOx vs R-GemOx in R/R DLBCL 2. SUNMO Trial - Mosunetuzumab + Polatuzumab vs R-GemOx in R/R DLBCL 3. STARGLO Trial - Glofitamab + GemOx vs R-GemOx in R/R DLBCL (2-Year Update) 4. EPCORE NHL-5 & NHL-7 - Epcoritamab Combinations in Frontline DLBCL 5. EPCOR-RICE - Epcoritamab + R-ICE in Transplant-Eligible R/R DLBCL 6. LOTIS-7 Trial - Loncastuximab + Glofitamab in R/R DLBCL 7. Additional Studies Mentioned: R-Pola-Glo Frail Study DLBCL Classification

People in this episode

Hosts: Rajshekhar Chakraborty, Ashwin Kishtagari, Edward Cliff

Guest: Dr. Adrian Minson

Topics covered

• lymphoma updates
• clinical trials
• bispecific antibodies
• diffuse large B-cell lymphoma
• cancer treatment
• EHA and ICML meetings

Keywords

• lymphoma
• clinical trials
• bispecific antibodies
• DLBCL
• EHA
• ICML
• cancer treatment

Mentioned in this episode

Organizations: Peter MacCallum Cancer Centre

Products: bispecific antibodies, Polatuzumab, R-GemOx, Mosunetuzumab, Glofitamab, Epcoritamab, Loncastuximab

Books & works: diffuse large B-cell lymphoma (DLBCL)

More episodes of Blood Cancer Talks

• Episode 70. ASH 2025 Myeloid Neoplasm Roundup with Dr. Curtis Lachowiez · February 27, 2026 · 57 min
• Episode 69. ASH 2025 Lymphoma Roundup with Dr. Carla Casulo · January 22, 2026 · 44 min
• Episode 68. ASH 2025 Myeloma Special: MajesTEC-3 and the Bispecific Revolution with Dr. Luciano Costa · January 2, 2026 · 46 min
• Episode 67. Management of CMV in Hematologic Malignancies · November 23, 2025 · 40 min
• Episode 66. International Myeloma Society 2025 Annual Meeting Updates with Dr. Alfred Garfall: The Bispecific Bonanza · October 15, 2025 · 52 min
• Episode 65. Circulating Tumor DNA in DLBCL with Dr. Ash Alizadeh and Dr. David Russler-Germain · September 24, 2025 · 53 min

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