BI 242 Kathryn Nave: How Life Gets its Meaning and Intelligence

BI 242 Kathryn Nave: How Life Gets its Meaning and Intelligence

July 15, 2026 · 1h 45m

About this episode

Kathryn Nave discusses the limitations of the free energy principle and introduces the concept of organizational closure as a framework for understanding life and intelligence.

Support the show to get full episodes, full archive, and join the Discord community. The Transmitter is an online publication that aims to deliver useful information, insights and tools to build bridges across neuroscience and advance research. Visit thetransmitter.org to explore the latest neuroscience news and perspectives, written by journalists and scientists. Read more about our partnership. Sign up for Brain Inspired email alerts to be notified every time a new Brain Inspired episode is released. To explore more neuroscience news and perspectives, visit thetransmitter.org. Kathryn Nave is a Leverhulme Trust Early Career Fellow at the University of Edinburgh, and the author of the book A Drive to Survive: The Free Energy Principle and the Meaning of Life. In the book, Kate dives deep into the free energy principle and active inference, which are popular approaches to studying brains, minds, and organisms in general, and which are being used in artificial intelligence. Ultimately, Kate finds these approaches come up short as explanatory frameworks for life, and autonomy, and intelligence. Instead, Kate and many others advocate a framework that Kate calls constraint closure or…

People in this episode

Host: Paul Middlebrooks

Guest: Kathryn Nave

Mentioned in this episode

Organizations: University of Edinburgh, The Transmitter

Books & works: A Drive to Survive: The Free Energy Principle and the Meaning of Life

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