Ep 167 Endometriosis Diagnosis Without Surgery? Dr. Bruce Lessey

Ep 167 Endometriosis Diagnosis Without Surgery? Dr. Bruce Lessey

From Brave & Curious with Dr Lora Shahine by Dr. Lora Shahine

March 24, 2026 · 46 min · Season 1 · Episode 167

About this episode

Dr. Lora Shahine discusses with Dr. Bruce Lessey the potential for diagnosing endometriosis without surgery through BCL6 testing.

Are you struggling with unexplained infertility and wondering if endometriosis could be the missing piece? Have you been told that surgery is the only way to get a diagnosis? What if a simple test could offer answers without going into the operating room? In this episode of Brave & Curious, Dr. Lora Shahine welcomes guest Dr. Bruce Lessey, a double board certified OBGYN and Reproductive Endocrinologist with decades of research experience and over 150 peer-reviewed publications. Together they explore a groundbreaking question in reproductive medicine: can we diagnose endometriosis without invasive surgery? Dr. Lessey and Dr. Shahine explain the science behind BCL6 testing, a biomarker found in the uterine lining that may signal inflammation linked to endometriosis. Dr. Lessey also shares how this research evolved from studying implantation markers to developing a potential non-invasive diagnostic tool, and why timing in the menstrual cycle is critical for accurate results. They also discuss the realities of delayed diagnosis, the connection between endometriosis and unexplained infertility, and how this test is already being used in clinical settings. In this episode you'll hear…

People in this episode

Host: Dr. Lora Shahine

Guest: Dr. Bruce Lessey

Topics covered

  • endometriosis
  • infertility
  • diagnosis
  • reproductive medicine
  • BCL6 testing
  • non-invasive testing

Keywords

  • endometriosis
  • infertility
  • BCL6 testing
  • non-invasive diagnosis
  • reproductive endocrinology
  • surgery alternatives

Mentioned in this episode

Organizations: BCL6, IVF

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