
Ep 167 Endometriosis Diagnosis Without Surgery? Dr. Bruce Lessey
From Brave & Curious with Dr Lora Shahine by Dr. Lora Shahine
March 24, 2026 · 46 min · Season 1 · Episode 167
About this episode
Dr. Lora Shahine discusses with Dr. Bruce Lessey the potential for diagnosing endometriosis without surgery through BCL6 testing.
Are you struggling with unexplained infertility and wondering if endometriosis could be the missing piece? Have you been told that surgery is the only way to get a diagnosis? What if a simple test could offer answers without going into the operating room? In this episode of Brave & Curious, Dr. Lora Shahine welcomes guest Dr. Bruce Lessey, a double board certified OBGYN and Reproductive Endocrinologist with decades of research experience and over 150 peer-reviewed publications. Together they explore a groundbreaking question in reproductive medicine: can we diagnose endometriosis without invasive surgery? Dr. Lessey and Dr. Shahine explain the science behind BCL6 testing, a biomarker found in the uterine lining that may signal inflammation linked to endometriosis. Dr. Lessey also shares how this research evolved from studying implantation markers to developing a potential non-invasive diagnostic tool, and why timing in the menstrual cycle is critical for accurate results. They also discuss the realities of delayed diagnosis, the connection between endometriosis and unexplained infertility, and how this test is already being used in clinical settings. In this episode you'll hear…
People in this episode
Host: Dr. Lora Shahine
Guest: Dr. Bruce Lessey
Topics covered
- endometriosis
- infertility
- diagnosis
- reproductive medicine
- BCL6 testing
- non-invasive testing
Keywords
- endometriosis
- infertility
- BCL6 testing
- non-invasive diagnosis
- reproductive endocrinology
- surgery alternatives
Mentioned in this episode
Organizations: BCL6, IVF
More episodes of Brave & Curious with Dr Lora Shahine
- Ep 171 What Your Semen Analysis is Not Telling You with Jeff Lysiak, PhD · May 5, 2026 · 36 min
- Ep 170 Cost of Fertility Care: Solutions with Angela Rastegar from Sunfish · April 22, 2026 · 38 min
- BONUS Ep 169 Fighting for Fertility with RESOLVE CEO Danielle Melfi · April 19, 2026 · 41 min
- Ep 168 Taking Charge of Your PCOS with Cory Ruth, RDN · April 7, 2026 · 46 min
- Ep 166 Is Inflammation Hijacking Your Fertility? Answers from Natalie Crawford, MD · March 10, 2026 · 56 min
- Ep 165 Do Progesterone Shots Improve Frozen Embryo Transfer Success? · March 3, 2026 · 17 min
Explore listener stats, chart rankings, contacts and more on the Brave & Curious with Dr Lora Shahine podcast page.