#132 – Complicated UTIs: What’s Crystal Clear & What’s Still Cloudy

About this episode

The episode discusses the complexities of complicated urinary tract infections and the latest updates in treatment and management.

Episode Notes Complicated UTIs just got a whole lot less complicated—or did they? Dr. Dana Bowers and Kyle Molina (@kcmolinaID) join Dr. Whitney Buckel to break down what’s new, what’s controversial, and what this means for your day‑to‑day antimicrobial decisions. Join us as we dig into the biggest updates, the evidence behind them, and the clinical pearls you won’t want to miss. References: Nelson Z, Aslan AT, Beahm NP, et al. Guidelines for the Prevention, Diagnosis, and Management of Urinary Tract Infections in Pediatrics and Adults: A WikiGuidelines Group Consensus Statement. JAMA Netw Open. 2024 Nov 4;7(11):e2444495. Trautner BW, Cortes-Penfield NW, Gupta K, et al. Complicated Urinary Tract Infections (cUTI): Clinical Guidelines for Treatment and Management. Published July 17, 2025. https://www.idsociety.org/practice-guideline/complicated-urinary-tract-infections/ Kadry N, Natarajan M, Bein E, Kim P, Farley J. Discordant Clinical and Microbiological Outcomes Are Associated With Late Clinical Relapse in Clinical Trials for Complicated Urinary Tract Infections. Clin Infect Dis 2023;76(10:1768-1775. https://academic.oup.com/cid/article/76/10/1768/6980780 USCAST Oral…

People in this episode

Host: Dr. Whitney Buckel

Guests: Dr. Dana Bowers, Kyle Molina

Topics covered

• Complicated UTIs
• Antimicrobial decisions
• Clinical guidelines
• Evidence-based medicine
• Updates in treatment

Keywords

• complicated UTIs
• antimicrobial decisions
• clinical guidelines
• evidence
• treatment updates

Mentioned in this episode

Organizations: Society of Infectious Diseases Pharmacists

Books & works: Guidelines for the Prevention, Diagnosis, and Management of Urinary Tract Infections in Pediatrics and Adults: A WikiGuidelines Group Consensus Statement, Complicated Urinary Tract Infections (cUTI): Clinical Guidelines for Treatment and Management, Discordant Clinical and Microbiological Outcomes Are Associated With Late Clinical Relapse in Clinical Trials for Complicated Urinary Tract Infections, A Cloudy Crystal Ball: Critically Assessing and Rethinking the Antibiogram

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