About this episode

This episode features expert discussions on the management of HR-Positive Breast Cancer from leading oncologists.

Featuring perspectives from Dr Erika Hamilton, Dr Jane Lowe Meisel, Dr Joyce O’Shaughnessy and Dr Seth Wander, including the following topics: Introduction (0:00) Current and Future Management of HR-Positive, HER2-Negative Localized Breast Cancer — Dr Meisel(2:40) Optimizing First-Line Therapy for Patients with HR-Positive Metastatic Breast Cancer (mBC) — Dr Hamilton (36:57) Current and Future Role of Oral Selective Estrogen Receptor Degraders for Progressive HR-Positive mBC — Dr Wander (58:18) Clinical Utility of Agents Targeting the PI3K/AKT/mTOR Pathway for Patients with Progressive HR-Positive mBC — Dr O'Shaughnessy (1:18:00) CME information and select publications

People in this episode

Host: Dr Neil Love

Guests: Dr Erika Hamilton, Dr Jane Lowe Meisel, Dr Joyce O’Shaughnessy, Dr Seth Wander

Topics covered

• HR-Positive Breast Cancer
• HER2-Negative Localized Breast Cancer
• First-Line Therapy for Metastatic Breast Cancer
• Oral Selective Estrogen Receptor Degraders
• PI3K/AKT/mTOR Pathway

Keywords

• breast cancer
• HR-Positive
• metastatic breast cancer
• treatment
• oncology
• estrogen receptor
• clinical utility

Mentioned in this episode

Organizations: National General Medical Oncology Summit

More episodes of Breast Cancer Update

• HER2-Positive Metastatic Breast Cancer — An Interview with Prof Dr Sibylle Loibl on First-Line and Maintenance Therapy · July 18, 2026 · 46 min
• Localized HR-Positive Breast Cancer — Year in Review Series on Relevant New Datasets and Advances · July 13, 2026 · 58 min
• For Oncology Nurses: Strategies to Safely and Effectively Implement Antibody-Drug Conjugates — Proceedings from the 2026 Annual ONS Congress · July 10, 2026 · 1h 29m
• Antibody-Drug Conjugates in the Management of Breast Cancer — Proceedings from a Session Held in Conjunction with the 2026 ASCO Annual Meeting · July 8, 2026 · 2h 0m
• Metastatic Triple-Negative Breast Cancer — What Clinicians Want to Know · June 26, 2026 · 54 min
• HER2-Positive Breast Cancer — Fifth Annual National General Medical Oncology Summit · June 23, 2026 · 52 min

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