Episode 154: Is Seed Based Cultivation the Future of Cannabis? - with Dr. Matthew Indest

Episode 154: Is Seed Based Cultivation the Future of Cannabis? - with Dr. Matthew Indest

December 10, 2025 · 1h 26m · Episode 154

About this episode

This episode explores the potential shift from clone-based to seed-based cannabis cultivation with insights from Dr. Matthew Indest.

Seed-grown cannabis has been talked about for years, but most commercial growers still lean on clones for consistency. In this episode, Dr. Matthew Indest and I dig into whether the industry is finally approaching a true shift. We unpack the science, the barriers, and the practical realities: genetic stability, uniformity, agronomic traits, pathogen concerns, breeding strategies, and the economics behind large-scale seed adoption. Dr. Indest brings a rare mix of rigorous plant science and real-world cannabis experience. If you’ve wondered whether seed-based cultivation can match or even outperform clonal systems — or what breeders actually need to deliver for that future to happen — this episode lays it out clearly.

People in this episode

Host: Tad Hussey

Guest: Dr. Matthew Indest

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