About this episode

The episode discusses systemic thrombolysis in pulmonary embolism with expert Dr. Allison Burnett, focusing on indications, candidate selection, and management strategies.

CardioNerds Drs. Dinu Balanescu , Billy-Joe Mullinax , and Mariana Garcia discuss systemic thrombolysis in pulmonary embolism with expert Dr. Allison Burnett . Audio editing by CardioNerds Academy intern, student doctor, Pace Wetstein . Pulmonary embolism is the third leading cause of cardiovascular death in the US, and high-risk PE carries a 30-day mortality risk as high as 30-50%. In this episode, we discuss the indications for systemic thrombolysis, including high-risk PE and cardiac arrest. We addressed how to appropriately select candidates for systemic thrombolysis, balancing the high risk of bleeding. Additionally, we discussed anticoagulation management and timing concurrent with lytic therapy, as well as the importance of multidisciplinary PERT teams.  The 2026 American multi-society PE guidelines were published after this episode was recorded. Dr. Dinu Balanescu and Dr. Billy-Joe Mullinax are Co-chairs for the CardioNerds PE Series, developed in collaboration with the PERT Consortium . Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Pulmonary Embolism Page CardioNerds Episode Page…

People in this episode

Hosts: Dr. Dinu Balanescu, Dr. Billy-Joe Mullinax

Guest: Dr. Allison Burnett

Topics covered

• pulmonary embolism
• systemic thrombolysis
• cardiovascular health
• anticoagulation management
• multidisciplinary teams
• risk stratification

Keywords

• pulmonary embolism
• thrombolysis
• cardiac arrest
• bleeding risk
• anticoagulation
• PERT teams
• ESC guidelines

Mentioned in this episode

Organizations: CardioNerds Academy, PERT Consortium, CardioNerds

Books & works: Circulation 2022 Paths to Discovery, CardioNerds Pulmonary Embolism Page, CardioNerds Episode Page, CardioNerds Academy, CardioNerds Healy Honor Roll, CardioNerds Journal Club, The Heartbeat Newsletter, CardioNerds SWAG, CardioNerds Patron

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