About this episode

The episode discusses obesity-related heart failure with preserved ejection fraction and therapeutic advances in metabolic modulation.

CardioNerds Dr. Rohit Nathani , Dr. Atefeh Ghorbanzadeh , and Dr. Mariam Riad , discuss Obesity-related Heart Failure with Preserved Ejection Fraction (HFpEF) with Dr. John Ostrominski. This episode was produced as part of the CardioNerds Academy curriculum by House Jones under the guidance of House Chief, Dr. Mariam Riad and Academy Program Director, Dr. Gurleen Kaur . A matching review article will be published in US Cardiology Review , the official journal of CardioNerds. This episode highlights the diverse clinical phenotypes and complex, multifaceted pathophysiology of HFpEF. We take a deep dive into the therapeutic advances that represent paradigm shift in metabolic modulation aimed at improving outcomes in patients with HFpEF and metabolic syndrome. Audio editing by CardioNerds intern Pacey Wetstein . Enjoy this Circulation Paths to Discovery article to learn more about the CardioNerds mission and journey. US Cardiology Review is now the official journal of CardioNerds! Submit your manuscripts here. CardioNerds Heart Success Series Page CardioNerds Episode Page CardioNerds Academy Cardionerds Healy Honor Roll CardioNerds Journal Club Subscribe to The Heartbeat Newsletter…

Topics covered

• Heart Failure with Preserved Ejection Fraction
• Metabolic Syndrome
• Obesity-related Heart Failure
• Therapeutic Advances
• Clinical Phenotypes
• Pathophysiology

More episodes of Cardionerds: A Cardiology Podcast

• 463. Multimodality Imaging in Chronic Coronary Artery Disease with Dr. Panithaya Chareonthaitawee · August 17, 2026 · 40 min
• 462. Tricuspid Regurgitation with Dr. Sunil Mankad · August 13, 2026 · 19 min
• 461. Pre-Pregnancy Risk Stratification and Counseling with Dr. Katie Young · August 11, 2026 · 52 min
• 459. The Continuum of Prevention and Heart Failure with Dr. Anu Lala and Dr. Martha Gulati · July 23, 2026 · 27 min

Explore listener stats, chart rankings, contacts and more on the Cardionerds: A Cardiology Podcast podcast page.