Semaglutide Becomes the First ORAL GLP-1 Approved for Weight Loss

Semaglutide Becomes the First ORAL GLP-1 Approved for Weight Loss

April 14, 2026 · 15 min · Season 2 · Episode 7

About this episode

This episode discusses the approval of semaglutide as the first oral GLP-1 agonist for weight loss and its implications for treatment.

A new oral option is changing the GLP-1 landscape for weight loss, along with raising questions about efficacy, dosing, and when switching products makes sense. In this episode, TRC Healthcare Associate Editor and Clinical Pharmacist Vickie Danaher, PharmD discusses how semaglutide became the first FDA-approved oral GLP-1 agonist for obesity. She breaks down how it works, how it compares to injectable options, and dosing considerations for patients. Vickie also walks through key counseling po...

People in this episode

Host: Vickie Danaher

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Mentioned in this episode

Organizations: FDA, TRC Healthcare

Products: semaglutide

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