Cardiorenal Metabolic Disease (15 Dec 2025)

Cardiorenal Metabolic Disease (15 Dec 2025)

From Clinical Conversations by Royal College of Physicians of Edinburgh

December 15, 2025 · 24 min

About this episode

Dr Marilena Giannoudi discusses cardiorenal metabolic disease with Dr Andrew Frankel, focusing on management strategies and the importance of lifestyle changes.

In this episode of Clinical Conversations, Dr Marilena Giannoudi discusses cardiorenal metabolic disease with Dr Andrew Frankel. Their discussion provides an overview of this common cause of chronic kidney disease (CKD) and they focus on the management of cardiorenal metabolic disease, with Dr Frankel highlighting the importance of lifestyle management and patient education and engagement, and the pharmacotherapy 'four pillars' of RAAS inhibition, SGLT2 inhibition, blood pressure control, and MR antagonism. Explore this and more in this episode. Dr Andrew Frankel has been working as a consultant nephrologist at Imperial College Healthcare NHS trust since 1995 and works at the Imperial Renal and Transplant Centre, which is one of the largest kidney units in Europe catering for a population base of over three million. He has experience in managing all aspects of kidney disease but has a particular interest in relation to the management of kidney disease in the context of diabetes, cardiac disease and obesity. Dr Marilena Giannoudi is a cardiology registrar based in Leeds. She is Co-Chair of RCPE's Trainees and Members' Committee. -- Links -- NICE Guideline (NG203) - Chronic kidney…

People in this episode

Guests: Dr Marilena Giannoudi, Dr Andrew Frankel

Topics covered

  • cardiorenal metabolic disease
  • chronic kidney disease
  • lifestyle management
  • patient education
  • pharmacotherapy

Keywords

  • cardiorenal metabolic disease
  • chronic kidney disease
  • lifestyle management
  • patient education
  • RAAS inhibition
  • SGLT2 inhibition
  • blood pressure control
  • MR antagonism

Mentioned in this episode

Organizations: Imperial College Healthcare NHS trust, Imperial Renal and Transplant Centre, Royal College of Physicians of Edinburgh

Books & works: NICE Guideline (NG203), 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes

More episodes of Clinical Conversations

Explore listener stats, chart rankings, contacts and more on the Clinical Conversations podcast page.