About this episode

The episode explores the application of PK/PD data in clinical practice with insights from experts.

In this episode of Communicable , Thomas Tängdén and Rekha Pai Mangalore return for part 2 of the ‘We will make you love PK/PD’ series. In this round, they are joined by Iris Minichmayr (Austria) and Phil Selby (Australia) for a deep dive into how PK/PD data and principles can be used as integral clinical tools to support dosing decisions. They break down technical concepts of pharmacometrics such as population PK models, Monte Carlo simulations, probability of target attainment (PTA), and cumulative fraction of response (CFR), helping to make these approaches more accessible to everyday clinical practice. This episode was edited by Kathryn Hostettler. The executive producer of Communicable is Angela Huttner. Further reading Tängdén T, et al. Personalised patient management and infection prevention: current evidence and future perspectives. In: ESCMID Global 2025. Available on ESCMID Media: https://media.escmid.org/videos/01K7HWCJAHZ464H3XXK97SZ842

People in this episode

Hosts: Thomas Tängdén, Rekha Pai Mangalore

Guests: Iris Minichmayr, Phil Selby

Topics covered

• PK/PD
• pharmacometrics
• clinical tools
• dosing decisions
• population PK models
• Monte Carlo simulations

Keywords

• PK/PD
• pharmacometrics
• dosing decisions
• population PK models
• Monte Carlo simulations
• probability of target attainment
• cumulative fraction of response

Mentioned in this episode

Organizations: CMI Communications, ESCMID

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