#197 Hypercoagulability Part 2: 5 Pearls Segment
From Core IM | Internal Medicine Podcast by Core IM Team
January 7, 2026 · 38 min
About this episode
The episode discusses the management of hypercoagulability and the nuances of anticoagulation in various clinical scenarios.
Gray zones of VTE management! How to approach anticoagulation duration in unprovoked, provoked-irreversible, and provoked-reversible clots? When dose-reduced DOACs make sense for long-term secondary prevention? What truly constitutes DOAC failure? We also devle into how APLAS a critical do-not-miss diagnosis that changes management entirely. 🔹 Sponsor : Pain Management and Opioids Adaptive Learning Free Online Course by NEJM Group: https://cme-info.nejm.org/core-im/ 🔹 Transcript & Shownotes (2:56) - (13:15) | PEARL 1: Managing clots in the “unprovoked”/provoked-irreversible patient (13:21) - (18:10) | PEARL 2: Managing provoked, “reversible” clots (18:14) - (25:14) | PEARL 3: DOAC failure: time to step it up? (25:20) - (37:25) | PEARL 4: APLAS: the exception to everything Tags: CoreIM, Internal Medicine, ClinicalPearls, Medical Education, IMCore, hospitalist, physician assistant, nurse practitioner, medical student, internal medicine, hematology Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840 Our Sponsors: * Check out Quince: https://quince.com/coreim * Use code FIGSRX for 20% off: https://wearfigs.com Advertising…
Topics covered
- VTE management
- anticoagulation
- DOACs
- APLAS
- clot management
Keywords
- CoreIM
- Internal Medicine
- ClinicalPearls
- Medical Education
- IMCore
- hospitalist
- physician assistant
- nurse practitioner
- medical student
- internal medicine
- hematology
Sponsors
NEJM Group, Pattern Life, Quince
Mentioned in this episode
Products: DOACs
More episodes of Core IM | Internal Medicine Podcast
- #209 Dialysis and Fluid Management: 5 Pearls Segment · June 10, 2026 · 32 min
- #208 AI vs. Human with Post-Op AFib: Bread & Butter Series · May 27, 2026 · 29 min
- #207 Is There a Doctor on Board? In-Flight Emergencies · May 18, 2026 · 28 min
- #206 Eosinophilia: 5 Pearls Segment · April 28, 2026 · 43 min
- #205 Nutrition Studies, Coffee and the CRAVE Trial: Beyond Journal Club with the NEJM Group · April 15, 2026 · 32 min
- #204 Diabetic Foot Infections & Osteomyelitis: 5 Pearls Segment · April 1, 2026 · 34 min
Explore listener stats, chart rankings, contacts and more on the Core IM | Internal Medicine Podcast podcast page.