Can You Reverse Decades of Drinking Damage? Perhaps. - EP 75 Jacob Kimmel Is Back

Can You Reverse Decades of Drinking Damage? Perhaps. - EP 75 Jacob Kimmel Is Back

From Core Memory by Ashlee Vance

June 2, 2026 · 2h 0m · Episode 75

About this episode

Jacob Kimmel discusses potential therapies to reverse alcohol-related damage and the intersection of AI and biology.

Jacob Kimmel returns to the show. And he might have cured the hangover and liver disease. NBD. Kimmel is the co-founder and president of NewLimit and one of the deepest thinkers in the longevity field. His company has been working to reverse the aging process in the body and has seen some stunning results with a new therapy that undoes liver damage in mice. We’re talking old mice that shrug off the effects of too much booze as if they were teenagers and that exhibit recoveries from long-term alcohol abuse. The results have been good enough to help NewLimit raise another $435 million from the likes of Founders Fund and Thrive Capital. They’re also good enough to have NewLimit kick off a human trial of the therapy next year. And I’ll drink to that. We discuss all of this on the podcast and then go much deeper on the longevity field, bio-tech and the collision of AI and biology. The Core Memory podcast is on all major platforms and on our YouTube channel over here . If you like the show, please leave a review and tell your friends. OUR SPONSORS SendCutSend Do you make stuff? Do you need metal parts fast and believe in truth and justice? Then head on over to SendCutSend where you’ll…

People in this episode

Host: Ashlee Vance

Guest: Jacob Kimmel

Topics covered

  • longevity
  • bio-tech
  • alcohol recovery
  • human trials
  • AI and biology

Keywords

  • hangover cure
  • liver disease
  • aging process
  • therapy
  • human trial

Sponsors

SendCutSend, Brex

Mentioned in this episode

Organizations: NewLimit, Founders Fund, Thrive Capital

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