Beyond the Prescription Pad: The Clinical Power of OTC Skin Care

Beyond the Prescription Pad: The Clinical Power of OTC Skin Care

From Cutaneous Miscellaneous: The Dermatology Residents Podcast by Dermsquared

March 4, 2026 · 31 min · Season 6 · Episode 48

About this episode

The episode discusses the clinical role of over-the-counter skin care products in dermatology practice.

In this episode of Cutaneous Miscellaneous, host Nicholas Brownstone, MD, welcomes Peter Lio, MD, to examine the role of over-the-counter (OTC) skin care in everyday practice. They discuss evolving perceptions of “drugstore” products, explore what “sensitive skin” may actually represent clinically, and review emerging data on polymer-based cleansing technologies designed to support barrier integrity. The conversation also highlights formulation science, including research evaluating moisturizers that combine hyaluronic acid, natural moisturizing factors, and essential lipids, as well as data suggesting improved quality of life when lightweight adjunctive moisturizers are paired with acne regimens. They also examine clinical findings from a study assessing structured OTC regimens before and after procedures and their impact on tolerability and irritation. Tune in to the episode for an evidence-informed framework for recommending OTC products with confidence and elevating everyday patient care as a resident or early-career dermatologist.

People in this episode

Host: Nicholas Brownstone, MD

Guest: Peter Lio, MD

Topics covered

  • over-the-counter skin care
  • formulation science
  • sensitive skin
  • polymer-based cleansing technologies
  • moisturizers
  • acne regimens
  • patient care

Keywords

  • OTC skin care
  • sensitive skin
  • moisturizers
  • hyaluronic acid
  • acne regimens
  • barrier integrity
  • clinical findings

Mentioned in this episode

Organizations: Cutaneous Miscellaneous, Dermsquared

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