Ep. 18 — Peptide Deep Dive, Met Gala Skin Moments & Skin Tightening in the GLP-1 Era

About this episode

The episode explores peptides, skin tightening devices, and highlights from the Met Gala 2026.

Episode 18 of Derm Next Door is a packed one. We're breaking down the peptide conversation from every angle — what signal peptides, neuropeptides, and carrier peptides are actually doing to your skin at the cellular level, how topical delivery compares to injectable peptides, and which ones have real clinical backing vs. just good marketing. In What We're Side-Eyeing, we get into PP405 — the hair loss drug everyone is talking about. Phase 2a data just dropped, and we have thoughts on what the results actually show, what's still missing, and why the hype might be getting ahead of the science. Then we hit the Met Gala 2026 red carpet. The Devil Wears Prada theme brought out Anne Hathaway, Emily Blunt, Rihanna, Hailey Bieber, and more — and we're talking skin, glow, possible tweakments, and the beauty moments that stood out (for better or worse). Segment 3 is for everyone currently on a GLP-1 or treating patients who are: we break down the major skin tightening devices — Morpheus8, Ultherapy, Sofwave, Thermage, and Emface — what they actually do, how they compare, and who each one is best for when laxity is the chief complaint. And we close with our Products of the Month: Reem is…

People in this episode

Hosts: Ali Dempsey, Reem Nabti

Topics covered

• peptides
• skin tightening
• Met Gala
• hair loss
• skin care products

Keywords

• peptides
• skin tightening
• Met Gala
• PP405
• skin care

Mentioned in this episode

Organizations: Morpheus8, Ultherapy, Sofwave, Thermage, Emface

Products: La Roche-Posay Cicaplast B5 Spray, L'Oréal EverPure Bond Repair, Eadem Lip Balm, Summer Fridays Jet Lag Eye Patches, SkinCeuticals P-TIOX, PP405

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