Beatriz Colomina and Mark Wigley on Biotic Architecture

Beatriz Colomina and Mark Wigley on Biotic Architecture

From Design Emergency by Alice Rawsthorn and Paola Antonelli

February 4, 2026 · 38 min · Season 6 · Episode 3

About this episode

Beatriz Colomina and Mark Wigley discuss the role of bacteria in architecture and the implications for design practices.

Architecture has long treated bacteria as an enemy to be controlled—dangerous foreign agents to be sealed out, sterilized, or erased. In their new book,  We the Bacteria: Notes Toward a Biotic Architecture , architecture historians and curators  Beatriz Colomina  and  Mark Wigley  turn that assumption inside out (literally,) arguing that architecture should not be bent on shielding and isolating humans from their invisible partners through hygiene protocols, ventilation, materials, light, and other forms of management and control. Buildings should instead be shaped by microbes as they have been for centuries, and humans should reconsider their role as participants in a much larger biological collective. In this conversation with Paola, Beatriz and Mark explore how bacteria offer a radical lens through which to reinterpret architectural history and design practice. Rather than asking how architecture can protect us from microbes,  We the Bacteria  asks what it means to design for coexistence, and what political, ethical, and spatial fantasies are exposed when the dream of separation finally collapses. You can find images related to this interview…

People in this episode

Host: Paola Antonelli

Guests: Beatriz Colomina, Mark Wigley

Topics covered

  • biotic architecture
  • microbes
  • design for coexistence
  • architectural history
  • political implications of design

Keywords

  • architecture
  • bacteria
  • design
  • coexistence
  • hygiene protocols
  • biological collective
  • political fantasies

Mentioned in this episode

Organizations: Design Emergency

Books & works: We the Bacteria: Notes Toward a Biotic Architecture

More episodes of Design Emergency

Explore listener stats, chart rankings, contacts and more on the Design Emergency podcast page.