Women, Hormones & Cholesterol: The Hidden Role of Ultra-Processed Foods

Women, Hormones & Cholesterol: The Hidden Role of Ultra-Processed Foods

From Dr. Brendan McCarthy by Dr. Brendan McCarthy

April 30, 2026 · 17 min · Episode 188

About this episode

This episode discusses the often overlooked issue of cardiovascular disease in women, emphasizing the impact of ultra-processed foods and the importance of addressing cholesterol management during menopause.

Today, we’re diving into a topic that should be getting far more attention: Cardiovascular disease in women. Heart disease is one of the leading causes of death in women—yet it’s often under-addressed, oversimplified, and misunderstood in clinical practice. Most women are told:“Eat better. Take this prescription.” But that approach misses something critical. Full citation list: • Hall, Kevin D., et al. “Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake.” Cell Metabolism, vol. 30, no. 1, 2019, pp. 67–77.e3. Supports the core causal point that ultra-processed foods drive higher intake and weight gain even under controlled feeding conditions; this is not a women-specific lipid paper, but it is the cleanest experimental anchor for why UPFs create a high-throughput metabolic environment. • El Khoudary, Samar R., et al. “Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association.” Circulation, vol. 142, no. 25, 2020, pp. e506–e532. Supports the midlife women’s frame: across the menopause transition, LDL-C…

People in this episode

Host: Dr. Brendan McCarthy

Topics covered

  • Cardiovascular disease in women
  • Ultra-processed foods
  • Menopause and heart health
  • Cholesterol management
  • Women's health
  • Dietary impacts on health

Keywords

  • cardiovascular disease
  • women's health
  • ultra-processed foods
  • cholesterol
  • menopause
  • diet
  • heart disease

Mentioned in this episode

Organizations: American Heart Association

Books & works: Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake, Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association

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