Environment. Epigenome. Early Colorectal Cancer. 🌍🧬🧫

Environment. Epigenome. Early Colorectal Cancer. 🌍🧬🧫

From Dr RR Baliga's "Got Knowledge Doc" Podkast by Dr RR Baliga, MD, MBA

May 3, 2026 · 7 min

About this episode

The episode discusses how environmental exposures impact the epigenome and are linked to early-onset colorectal cancer.

🧬⚠️ Genes. Toxins. Tumors. A compelling Nature Medicine study uncovers how the exposome—our lifetime environmental exposures—leaves epigenetic fingerprints linked to early-onset colorectal cancer . 🚜 A striking signal: picloram exposure shows consistent association across cohorts and real-world US data. 📊 Reinforces known risks (smoking, diet, education) while revealing novel environmental drivers . 💡 The message is clear: cancer prevention may begin far upstream—in policy, environment, and early-life exposures. #ColorectalCancer #Exposome #Epigenetics #PrecisionMedicine #PublicHealth

People in this episode

Host: Dr RR Baliga

Topics covered

  • epigenetics
  • colorectal cancer
  • environmental exposures
  • cancer prevention
  • public health

Keywords

  • epigenome
  • exposome
  • early colorectal cancer
  • picloram
  • cancer prevention
  • environmental toxins
  • public health

Mentioned in this episode

Organizations: Nature Medicine, PublicHealth

Products: picloram

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