Ep. 203: Diagnostic challenges in ALS and frontotemporal dementia

About this episode

This episode discusses the diagnostic challenges in amyotrophic lateral sclerosis and frontotemporal dementia with insights from experts in the field.

Moderator: Valentina Iuzzolino (Naples, Italy) Guest: Elka Stefanova (Belgrade, Serbia) and Mamede de Carvalho (Lisbon, Porugal) In this episode, Valentina Iuzzolino speaks with Elka Stefanova and Mamede de Carvalho about diagnostic challenges in amyotrophic lateral sclerosis and frontotemporal dementia. They discuss clinical heterogeneity, key differential diagnoses and red flags, the role of Gold Coast criteria and neurophysiology in ALS, and the importance of longitudinal clinical assessment and neuroimaging in distinguishing frontotemporal dementia from primary psychiatric disorders.

People in this episode

Host: Valentina Iuzzolino

Guests: Elka Stefanova, Mamede de Carvalho

Topics covered

• diagnostic challenges
• amyotrophic lateral sclerosis
• frontotemporal dementia
• clinical heterogeneity
• neuroimaging
• longitudinal clinical assessment

Keywords

• ALS
• frontotemporal dementia
• diagnosis
• neurophysiology
• Gold Coast criteria
• clinical assessment
• neuroimaging

Mentioned in this episode

Places: Naples, Italy, Belgrade, Serbia, Lisbon, Portugal

More episodes of eanCast: Weekly Neurology

• Ep. 204: Social Cognition in ALS – beyond motor neurons · June 7, 2026 · 13 min
• Ep. 202: Clinical neurology Meets AI: Are we prepared? · May 24, 2026 · 26 min
• Ep. 201: Inside the Black Box: Can Neurologists Trust AI? · May 17, 2026 · 22 min
• Ep. 200: Human versus artificial intelligence: the contest · May 10, 2026 · 34 min
• Ep. 199: AI Demystified: What It Is - and Isn’t · May 3, 2026 · 27 min
• Ep. 198: The Complex Interaction between (Social) Media and Functional Neurological Disorders · April 26, 2026 · 29 min