Harnessing MALDI-TOF for MICs

Harnessing MALDI-TOF for MICs

From Editors in Conversation by American Society for Microbiology

March 6, 2026 · 34 min · Episode 112

About this episode

The episode discusses the impact of MALDI-TOF mass spectrometry in clinical microbiology and its potential to replace traditional antimicrobial susceptibility tests.

Matrix-assisted laser desorption ionization time of flight mass spectrometry (or MALDI) has revolutionized the clinical microbiology laboratory, enabling rapid, accurate and cheap identification of bacteria, yeast, moulds and mycobacteria. In most labs, it has become a verb (I maldi'ed it). But – can it replace our antimicrobial susceptibility tests? Let's find out! Guests: Dr. Frieder Schaumburg Niklas Wiesmann

People in this episode

Guests: Dr. Frieder Schaumburg, Niklas Wiesmann

Topics covered

  • mass spectrometry
  • clinical microbiology
  • antimicrobial susceptibility testing
  • bacterial identification
  • yeast identification
  • fungal identification

Keywords

  • MALDI
  • mass spectrometry
  • clinical microbiology
  • bacteria identification
  • antimicrobial susceptibility
  • yeast
  • fungi
  • mycobacteria

Mentioned in this episode

Organizations: American Society for Microbiology

Products: MALDI-TOF

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