Rethinking Security from the OS Up in the Age of AI and more RSAC 2026 Interviews - Karen Heart, Sachin Jade, Phil Calvin, Craig Sanderson, Travis Wong - ESW #456

Rethinking Security from the OS Up in the Age of AI and more RSAC 2026 Interviews - Karen Heart, Sachin Jade, Phil Calvin, Craig Sanderson, Travis Wong - ESW #456

April 27, 2026 · 1h 36m

About this episode

Karen Heart discusses a file-system–first approach to security in the context of modern attacks and AI.

Rethinking Security from the OS Up in the Age of AI Karen Heart discusses a file-system–first approach to security, arguing that most modern attacks—including ransomware and supply chain compromises—succeed because they inherit user permissions and operate inside overly trusted system structures. She explains how limiting file access, socket (network) access, and privilege escalation at the operating system level can reduce entire classes of attacks. Rather than relying on reactive detection, her approach emphasizes immutable, allowlisted controls embedded close to the kernel layer, designed to prevent both data exfiltration and malicious code execution at the source. The conversation also explores how AI agents and contractors expand the attack surface, reinforcing the need for strict isolation, backup protection, and deterministic system boundaries. Segment Resources: https://www.simonandschuster.com/books/Zero-Day-Secure/Karen-Heart/9781968865078 ​The New Era of DNS Resilience: Breaking down the newly finalized NIST SP 800-81 Craig Sanderson from Infoblox will dive into the newly finalized NIST SP 800-81 as it marks a pivotal shift in DNS security, emphasizing resilience…

People in this episode

Host: Adrian Sanabria

Guests: Karen Heart, Craig Sanderson, Sachin Jade, Phil Calvin, Travis Wong

Topics covered

Keywords

Mentioned in this episode

Organizations: Infoblox, NIST

Books & works: Zero-Day-Secure

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