About this episode

The episode discusses the simultaneous use of Flozins and Finerenone in treating chronic kidney disease and type 2 diabetes.

The Filtrate Joel Topf @kidneyboy.bsky.social‬ Swapnil Hiremath @hswapnil.medsky.social Nayan Arora captainchloride.bsky.social Sopia Ambruso @sophia-kidney.bsky.social Special Guests Brendon Neuen @brendonneuen.bsky.social Associate Professor and Program Lead, Renal and Metabolic at The George Institute for Global Health. Nephrologist and Director of Kidney Trials at Royal North Shore Hospital. Neuen has had three prior appearances on Freely Filtered: EMPA Kidney , DUPLEX and Sparsentan in FSGS , FLOW and Semaglutide Muthiah Vaduganathan @mvaduganathan on X. Cardiologist at Brigham and Women's Hospital and Harvard Medical School. Assistant Professor of Medicine. Editing by Joel Topf The Kidney Connection written and performed by Tim Yau Show Notes DONATE to NephJC! Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes NEJM | NephJC Summary FIDELIO Bakris et al , NEJM 2020 | NephJC Summary ; subgroup throws doubt on efficacy of finerenone in patients on flozins FIGARO Pitt et al , NEJM 2021; subgroups clearly shows finerenone works, flozins or not NEJM editorial (wrongly) saying do not use Flozins unless on RASi  Don’t use dual RAS blockade ONTARGET…

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