93. Mehret Mandefro: Empowering Storytellers and Building Creative Infrastructure

93. Mehret Mandefro: Empowering Storytellers and Building Creative Infrastructure

November 13, 2025 · 46 min

About this episode

In this episode, Alex speaks with Mehret Mandefro about empowering storytellers and building creative infrastructure in the media landscape.

How do you build an entire creative ecosystem? And what does it take to empower storytellers at scale? In this episode, Alex speaks with Emmy-nominated producer, writer, doctor and serial entrepreneur Mehret Mandefro, a visionary voice at the intersection of storytelling, healing and creative innovation. As co-founder and MD of Realness Institute, Mehret has spent years strengthening Africa’s media landscape through training, mentorship and systemic infrastructure-building. She shares her remarkable journey from medicine to media, the origins of her “audiovisual medicine” artistic practice, and the powerful lessons learned from pioneering television in Ethiopia and developing talent across the continent. In a wide ranging conversation, Mehret also dives into: • Why creative infrastructure is the missing piece in global storytelling • How Realness Institute nurtures and de-risks new creative voices • The urgent need for producers to think like entrepreneurs • The role of technology and AI in elevating human stories • Why Africa is central to the future of film This is a conversation about creativity, systems change and the responsibility we all share in shaping the future of…

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