Journal club #8 | PROTECT and EV-301

Journal club #8 | PROTECT and EV-301

June 13, 2026 · 23 min

About this episode

The episode discusses significant findings from the PROTECT and EV-301 trials related to prostate and bladder cancer.

Welcome to Episode 8 of our monthly GU Cast Journal Club! Today we focus on two very important papers in localised prostate cancer and metastatic bladder cancer. The landmark 15 year update of the PROTECT trial, published in NEJM in 2023, and the breakthrough EV-301 trial which heralded enfortumab vedotin in progressive metastatic bladder cancer, published in NEJM in 2021. We are delighted to welcome back our GU Cast Journal Club Editors, Dr Carlos Delgado (Mexico City, MEX), and Dr Elena Be...

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