HFmrEF: Finding a Compass in the Heart Failure "No Man's Land"

HFmrEF: Finding a Compass in the Heart Failure "No Man's Land"

June 25, 2026 · 27 min · Season 3 · Episode 47

About this episode

This episode discusses the challenges and insights related to diagnosing and treating heart failure with mildly reduced ejection fraction (HFmrEF).

Heart failure with mildly reduced ejection fraction (HFmrEF) affects up to 25% of patients with heart failure, yet many clinicians remain uncertain about how best to diagnose and treat it. In this episode, HFSA Scientific Statement co-authors Jane E. Wilcox, MD, and Barry A. Borlaug, MD, discuss the evidence, clinical implications, and key takeaways from the newly published HFSA Scientific Statement. Read the Scientific Statement: HFSA Scientific Statement: Heart Failure with Mildly Reduced Ejection Fraction

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