MRAs in HFpEF & HFmrEF: A Clinical Debate

MRAs in HFpEF & HFmrEF: A Clinical Debate

From Heart Failure Beat by Heart Failure Society of America

March 26, 2026 · 36 min · Season 3 · Episode 45

About this episode

Heart failure pharmacists debate the role of MRAs in HFpEF and HFmrEF, discussing trial data and treatment options.

In this lively debate, heart failure pharmacists Stormi Gale, PharmD and Robert L Page II, PharmD examine the role of MRAs in HFpEF and HFmrEF. From trial data and cost considerations to CKM overlap and hyperkalemia risk, they explore whether finerenone represents a new pillar - or whether spironolactone remains the practical choice.

People in this episode

Guests: Stormi Gale, PharmD, Robert L Page II, PharmD

Topics covered

  • heart failure
  • clinical debate
  • MRAs
  • HFpEF
  • HFmrEF
  • pharmacology
  • trial data

Keywords

  • MRAs
  • HFpEF
  • HFmrEF
  • finerenone
  • spironolactone
  • hyperkalemia
  • clinical debate

Mentioned in this episode

Organizations: Heart Failure Society of America

Products: finerenone, spironolactone

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