Episode 131 - TXA: The Clot Thickens

Episode 131 - TXA: The Clot Thickens

From Heavy Lies the Helmet by Mike Boone, Dan Rauh, & Dr. Amanda Humphries

July 14, 2025 · 55 min · Season 1 · Episode 131

About this episode

This episode explores the use of Tranexamic Acid (TXA) in trauma and prehospital care, discussing its effectiveness and the evidence surrounding its application.

Tranexamic Acid (TXA) is a lot like hot sauce: People put it on everything — especially for apparent or suspected acute blood loss. In this podcast episode, we dive into a drug that's been both praised and questioned in trauma and prehospital care. We break down what TXA is, how it works, and the evidence behind its use. From CRASH-2 to CRASH-3, we explore the key studies, the controversies, and the real-world implications. Whether you're administering TXA in the back of a rig or evaluating its role in your protocols, this episode helps you make sense of when, why, and how TXA might—or might not—stop the bleeding. Get CE hours for our podcast episodes HERE ! -------------------------------------------- Twitter @ heavyhelmet Facebook @ heavyliesthehelmet Instagram @ heavyliesthehelmet Website heavyliesthehelmet.com Email contact@heavyliesthehelmet.com Disclaimer: Heavy Lies the Helmet's content is for educational purposes only and does not constitute medical advice. Always follow local guidelines and consult qualified professionals before applying any information. The hosts and guests are not responsible for errors, omissions, or outcomes. Views expressed are their own and do not…

People in this episode

Hosts: Mike Boone, Dan Rauh, Dr. Amanda Humphries

Topics covered

  • Tranexamic Acid
  • trauma care
  • prehospital care
  • blood loss
  • medical evidence
  • clinical protocols

Keywords

  • TXA
  • Tranexamic Acid
  • acute blood loss
  • trauma
  • CRASH studies
  • medical protocols
  • evidence-based medicine

Mentioned in this episode

Products: Tranexamic Acid (TXA)

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