Dr. Zach Bush: How the Microbiome Affects Metabolism, Brain Health, and Chronic Disease

Dr. Zach Bush: How the Microbiome Affects Metabolism, Brain Health, and Chronic Disease

August 13, 2026 · 1h 15m · Season 1 · Episode 89

About this episode

Dr. Zach Bush discusses the connection between the microbiome, chronic disease, and our disconnection from nature.

Join The Circle and use code "PODCAST": https://holplus.co/circle/ What if chronic disease, declining energy, cognitive issues, and fertility challenges are not isolated problems, but signs of a deeper disconnection from the natural world? In this episode of hol+ with Dr. Taz MD, Dr. Zach Bush explores the relationship between human health and the health of our environment. Drawing from his background in internal medicine, endocrinology, cancer research, and hospice care, he explains how his search for the root causes of disease led him from the hospital and laboratory to the microbiome, soil science, and regenerative agriculture. Dr. Bush describes mitochondria as essential generators of cellular energy and explains how the microbes living within and around us help support metabolism, immunity, neurological function, and communication throughout the body. He shares his perspective on how chemical agriculture, declining biodiversity, and changes in our food systems may be affecting these biological relationships. Dr. Taz and Dr. Bush also discuss the rise of obesity, insulin resistance, autoimmune disease, cognitive decline, chronic fatigue, and infertility. Dr. Bush presents his…

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