CME | Twisted Truths: What You Didn't Learn About Sickle Cell

CME | Twisted Truths: What You Didn't Learn About Sickle Cell

April 6, 2026 · 27 min · Season 1

About this episode

The episode discusses sickle cell disease and the role of family medicine in its management.

In this episode of CME On the Go , the hosts discuss sickle cell disease (SCD) and the role of family medicine in recognizing, screening, and preventing complications. They review SCD as an autosomal recessive hemoglobin disorder distinct from sickle cell trait and highlight major complications such as anemia, infection risk, pain crises, and acute chest syndrome. The episode emphasizes global prevalence, newborn screening (and potential gaps), and risk beyond African ancestry. It also covers hemoglobin electrophoresis patterns, preventive care including penicillin prophylaxis and vaccines, recommended screenings, preconception and genetic counseling, and the use, dosing, and monitoring of hydroxyurea. Learning Objectives Differentiate between sickle cell trait and disease and interpret screening results across the lifespan to guide patient and family education. Apply evidence-based screening recommendations and routine treatment strategies for sickle cell disease across the lifespan to support longitudinal care in primary care. The AAFP has reviewed Twisted Truths: What You Didn't Learn About Sickle Cell and deemed it acceptable for up to 0.50 Enduring Materials, Self-Study AAFP…

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