Dr. Eugene Manley Jr. | Cancer's Hidden Biology and the Research Bias Failing Patients
About this episode
Dr. Karlfeldt and Dr. Eugene Manley Jr. discuss the systemic exclusion of diverse populations in cancer research and its implications for treatment.
What if the cancer therapies being developed today simply weren't designed for you? In this episode of Integrative Cancer Solutions, Dr. K sits down with Dr. Eugene Manley Jr., molecular and cell biologist, cancer researcher, and founder of the SCHEQ Foundation, to unpack one of oncology's most overlooked problems: the systemic exclusion of diverse populations from the research that drives cancer care. Together, they explore the science of the tumor microenvironment, cancer stem cells, and why traditional chemotherapy often misses the mark. Dr. Manley also pulls back the curtain on a startling finding — that out of over 800 lung cancer cell lines studied, only 31 represented Black individuals — and what that means for the therapies being prescribed today. If you or someone you love is navigating cancer and wondering why the system feels like it wasn't built for you, this conversation is an important one. Key Takeaways: 0:00 Introduction 3:47 Tumor microenvironment and what drives cancer growth 7:04 Why a single biopsy can't capture the whole tumor 12:26 Cancer stem cells and chemotherapy resistance 18:00 Why women were excluded from biomedical research until 1993 20:00 The cell…
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