About this episode

This episode discusses the potential of identifying the right patients and endpoints to improve osteoarthritis treatment trials.

Can identifying the right patients and the right endpoints transform how we test new osteoarthritis treatments? On this week's episode of Joint Action, we unpack what the FNIH Biomarkers Consortium has learned so far, and how their latest phase aims to deliver biomarkers that can make disease-modifying OA drug trials smaller, faster, and more likely to succeed. Dr. Virginia Byers Kraus is a Professor of Medicine, Pathology, and Orthopaedic Surgery at Duke University School of Medicine. A rheumatologist and translational scientist, her research focuses on osteoarthritis and biomarker development as part of the international FNIH Biomarkers Consortium. Peter G. Mesenbrink, Ph.D., is Executive Director of Biostatistics at Novartis and industry co-chair of the FNIH Biomarkers Consortium. With expertise in adaptive trial design, surrogate endpoint development, and data sharing policy, he is a frequent collaborator across industry, regulatory, and academic communities. Dr. Jamie Collins is a biostatistician at Brigham and Women's Hospital and Associate Professor of Orthopaedic Surgery at Harvard Medical School. As lead statistician for the FNIH OA Biomarkers Consortium, her research…

People in this episode

Host: David Hunter

Guests: Dr Virginia Byers Kraus, Peter G. Mesenbrink, Dr Jamie Collins

Topics covered

• osteoarthritis
• biomarkers
• clinical trials
• drug development
• patient identification

Keywords

• osteoarthritis
• biomarkers
• clinical trials
• FNIH Biomarkers Consortium
• drug trials

Mentioned in this episode

Organizations: Duke University School of Medicine, FNIH Biomarkers Consortium, Novartis, Brigham and Women's Hospital, Harvard Medical School

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