Kidney Function Decline in Sickle Cell Disease: Associations with Renin Angiotensin System Inhibitors

Kidney Function Decline in Sickle Cell Disease: Associations with Renin Angiotensin System Inhibitors

May 28, 2026 · 9 min

About this episode

This episode discusses the lack of effective therapies for preserving kidney function in patients with sickle cell disease and the findings related to RAS inhibitors.

Sickle cell disease causes accelerated kidney function decline, yet proven GFR-preserving therapies remain elusive. In this study of adults with sickle cell disease, RASi use was not associated with a significant difference in the rate of eGFR decline.

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Keywords

Mentioned in this episode

Organizations: American Society of Nephrology

Products: Renin Angiotensin System Inhibitors

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