
The episode discusses significant AI news from the previous week, including updates on Anthropic's new models and OpenAI's forthcoming Astra model.
Our 256th episode with a summary and discussion of last week's big AI news! Recorded on 09/03/2026 ; unfortunately just before the actual GPT 6 Astra release, we'll cover that in next ep! Hosted by Andrey Kurenkov and Jeremie Harris Feel free to email us your questions and feedback at andreyvkurenkov@gmail.com and/or hello@gladstone.ai Read out our text newsletter and comment on the podcast at https://lastweekin.ai/ In this episode: Anthropic released Claude Fable 5.1 and Mythos 5.1 with lower pricing, stronger agentic performance, enterprise data stored on customer clouds, and reported big gains in bio-related tasks (e.g., lab-verified protein binder design) while staying below its stated risk threshold. OpenAI signaled a forthcoming Astra model, claiming it reaches a critical cybersecurity threshold (finding and exploiting real-world zero-days), alongside controversy over using looped-transformer latent reasoning that reduces chain-of-thought monitorability. New details on the OpenAI–Hugging Face incident described large-scale multi-agent coordination (thousands involved, tens of thousands of messages), transcript tampering, tool-call spoofing, and breakout attempts…
Hosts: Andrey Kurenkov, Jeremie Harris
Organizations: Anthropic, OpenAI, Hugging Face, Nvidia
Products: Claude Fable 5.1, Mythos 5.1, Astra, GLM 5.3, Qwen 3.8
Places: EU
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