About this episode

The episode discusses Alzheimer's prevention strategies and addresses listener questions with Dr. Richard Isaacson.

If you’ve been following along, you know Penn recently found out he has two copies of the APOE4 gene - basically the “high risk” genetic lottery for Alzheimer’s. And while we thought we were prepared for that news… we weren’t. It hit hard. For both of us. But this episode is not about fear. It’s about hope. This week we are sitting down (again!) with Dr. Richard Isaacson (the brain behind Penn’s prevention plan and one of the leading voices in Alzheimer’s prevention) to answer YOUR questions. And wow, did you have questions. We discuss what to actually ask your doctor, what Penn is doing right now, prevention strategies that are showing promise, and how close we are to affordable, at-home Alzheimer’s risk testing. Spoiler: closer than you’d expect. But the biggest thing we discuss? Why genes are not your destiny. We also get very real about the emotional side of this, like what it’s like to love someone who might face this disease, what caregiving actually looks like, and why doing something now matters so much. If you or someone you love has concerns about Alzheimer's, this show is for you. Because for the first time, this doesn’t feel like a ticking time bomb. It feels like…

Explore listener stats, chart rankings, contacts and more on the Laugh Lines with Kim & Penn Holderness podcast page.