Cardiovascular-Kidney-Metabolic (CKM) Syndrome

Cardiovascular-Kidney-Metabolic (CKM) Syndrome

June 30, 2026 · 30 min · Episode 673

About this episode

The episode discusses the interconnectedness of hypertension, diabetes, cardiovascular disease, and chronic kidney disease, introducing the concept of Kidney-Cardiovascular Metabolic Syndrome.

Host: Darryl S. Chutka, M.D. Guest: Regis Fernandes, M.D. We’ve known for some time that patients who have hypertension and diabetes are at increased risk for developing subsequent cardiovascular disease and chronic kidney disease. It’s now being thought that these health problems are related and interconnected, representing Kidney-Cardiovascular Metabolic Syndrome. They form a pathophysiologic triad driven by shared mechanisms where disease in one system accelerates dysfunction in the others. So, what does this mean for primary care clinicians? Traditionally, we’ve managed hypertension, diabetes, cardiovascular disease, and chronic kidney disease as separate health conditions. It’s now felt that there may be a better approach. The topic for this podcast is “Kidney-Cardiovascular Metabolic Syndrome”, and my guest is Dr. Regis Fernandes, a preventive cardiologist at the Arizona campus of the Mayo Clinic. We’ll discuss the science, clinical implications, and recommended management strategies for this health condition. Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development

People in this episode

Host: Darryl S. Chutka, M.D.

Guest: Regis Fernandes, M.D.

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Organizations: Mayo Clinic, Mayo Clinic School of Continuous Professional Development

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